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CLART PNEUMOVIR

CLART PneumoVir is a method of molecular biology which detects the presence of viruses that cause respiratory infections: Resp Syncytial Virus A+B, Rhinovirus , Parainfluenza virus 1+2+3+4, Metapneumovirus, Influenza virus A+Β+C, Enterovirus, Coronavirus, Type 229, Bocavirus, Adenovirus and in some cases (if the specific probe molecules are activated) it identifies the following respiratory viruses: Influenza virus H1N1+H3N2, Metapneumovirus A+B, Parainfluenza virus 4A+4B. Virus detection is performed by the amplification of the specific fragment of the viral genome via the PCR technique (polymerase chain reaction).

The amplification product is detected with the use of a new technological platform: CLART (Clinical Array Technology). The platform is based on low density micro-arrays placed at the bottom of the micro vial tube.

The advantages of the molecular method are:

  • High sensitivity: detection of 1 target molecule
  • High specificity: nature of nucleic acids
  • Quick Time: only a few hours
  • It detects pathogens even during the administration of antimicrobial treatment
  • It detects “difficult” microorgaisms (e.g. Influenza C, Parainfuenza 4a, Parainfluenza 4b, Rhinovirus, Echovirus, Metapneumovirus A, Metapneumovirus B, Bocavirus).

Clinical Arrays Technology also allows the detection of multiple infections, it is easy to implement and has objective result interpretation.


― Pneumoviruses & respiratory infections

Pneumoviruses affect all ages but mostly little children and older people.

Many viruses are seasonal and they are usually active during winter. They are transmitted via droplets and nasal secretions.

Respiratory viral infections affect different points in the respiratory tract from the nasal cavity to the lungs. They cause mainly the following diseases:

  • Common cold
  • Influenza
  • Pharyngitis & Laryngitis
  • Tracheitis
  • Brochiolitis & Bronchitis

The infections of the upper respiratory tract are the following: common cold, sinusitis, pharyngitis, laryngitis.

The infections of the lower respiratory tract are the following: Acute respiratory distress syndrome (ARDS), Infant respiratory distress syndrome (IRDS), asthma, emphysema, chronic bronchitis, pneumonia.


―  The viruses that cause respiratory tract infections are the following:

VIRUSESFREQUENCY
Rhinovirus30 – 50%
Coronavirus10 – 15%
Influenza5 – 15%
Parainfluenza5%
RSV5%
Adenovirus5%
Enterovirus5%
Metapneumovirus15%
Bocavirus20%


―  
Respiratory viruses and the symptoms they cause:

RhinitisRhinovirus
Coronavirus
RSV
Influenza A y B
Parainfluenza
Adenovirus
Enteroviruses
Coughing
Abundant nasal congestion
No temperature
RhinofaryngitisRSV
Influenza A y B
Adenoviruses
Rhinovirus
Sneezes
Abundant nasal congestion
Pharyngeal inflammation (Sore throat)
Coughing
Temperature (in occasions)
Laryngitis (faringoamigiti)Parainfluenza
Enteroviruses
Adenovirus
Rhinovirus
Pharyngeal inflammation (Sore throat)
Temperature
LaryngitisRSV
Influenza A y B
Parainfluenza
Rhinovirus
Coughing
Hoarseness or loss of voice
Noisy Inspirations
Temperature
Tracheo-bronchitisRSV
Influenza A y B
Parainfluenza
Adenoviruses
Coughing
Snore
Temperature
BronchitisRSV
Influenza A y B
Parainfluenza
Coronavirus
Whistles
Dyspnoea
Temperature
Broncho-pneumonitisRSV
Influenza A y B
Parainfluenza
Whistles
Alveolal Crepitations
Dyspnoea
Temperature
PneumoniaCoronavirus
RSV
Influenza A y B
Parainfluenza
Adenovirus
Alveolal Crepitations
Dyspnoea
Temperature

Βιβλιογραφία: http://www.nhs.uk/conditions/Respiratory-tract-infection/Pages/Introduction.aspx


For more information on CLART PneumoVir contact:
diagnostics@aenorasis.com


The information referred to for general information and informing the public and in any case can not replace a doctor or other suitably qualified health professional. The responsibility of the media carries by ENORASIS SA