CLART PNEUMOVIR
CLART PneumoVir is a method of molecular biology which detects the presence of viruses that cause respiratory infections: Resp Syncytial Virus A+B, Rhinovirus , Parainfluenza virus 1+2+3+4, Metapneumovirus, Influenza virus A+Β+C, Enterovirus, Coronavirus, Type 229, Bocavirus, Adenovirus and in some cases (if the specific probe molecules are activated) it identifies the following respiratory viruses: Influenza virus H1N1+H3N2, Metapneumovirus A+B, Parainfluenza virus 4A+4B. Virus detection is performed by the amplification of the specific fragment of the viral genome via the PCR technique (polymerase chain reaction).
The amplification product is detected with the use of a new technological platform: CLART (Clinical Array Technology). The platform is based on low density micro-arrays placed at the bottom of the micro vial tube.
The advantages of the molecular method are:
- High sensitivity: detection of 1 target molecule
- High specificity: nature of nucleic acids
- Quick Time: only a few hours
- It detects pathogens even during the administration of antimicrobial treatment
- It detects “difficult” microorgaisms (e.g. Influenza C, Parainfuenza 4a, Parainfluenza 4b, Rhinovirus, Echovirus, Metapneumovirus A, Metapneumovirus B, Bocavirus).
Clinical Arrays Technology also allows the detection of multiple infections, it is easy to implement and has objective result interpretation.
― Pneumoviruses & respiratory infections
Pneumoviruses affect all ages but mostly little children and older people.
Many viruses are seasonal and they are usually active during winter. They are transmitted via droplets and nasal secretions.
Respiratory viral infections affect different points in the respiratory tract from the nasal cavity to the lungs. They cause mainly the following diseases:
- Common cold
- Influenza
- Pharyngitis & Laryngitis
- Tracheitis
- Brochiolitis & Bronchitis
The infections of the upper respiratory tract are the following: common cold, sinusitis, pharyngitis, laryngitis.
The infections of the lower respiratory tract are the following: Acute respiratory distress syndrome (ARDS), Infant respiratory distress syndrome (IRDS), asthma, emphysema, chronic bronchitis, pneumonia.
― The viruses that cause respiratory tract infections are the following:
| VIRUSES | FREQUENCY |
|---|---|
| Rhinovirus | 30 – 50% |
| Coronavirus | 10 – 15% |
| Influenza | 5 – 15% |
| Parainfluenza | 5% |
| RSV | 5% |
| Adenovirus | 5% |
| Enterovirus | 5% |
| Metapneumovirus | 15% |
| Bocavirus | 20% |
― Respiratory viruses and the symptoms they cause:
| Rhinitis | Rhinovirus Coronavirus RSV Influenza A y B Parainfluenza Adenovirus Enteroviruses |
Coughing Abundant nasal congestion No temperature |
| Rhinofaryngitis | RSV Influenza A y B Adenoviruses Rhinovirus |
Sneezes Abundant nasal congestion Pharyngeal inflammation (Sore throat) Coughing Temperature (in occasions) |
| Laryngitis (faringoamigiti) | Parainfluenza Enteroviruses Adenovirus Rhinovirus |
Pharyngeal inflammation (Sore throat) Temperature |
| Laryngitis | RSV Influenza A y B Parainfluenza Rhinovirus |
Coughing Hoarseness or loss of voice Noisy Inspirations Temperature |
| Tracheo-bronchitis | RSV Influenza A y B Parainfluenza Adenoviruses |
Coughing Snore Temperature |
| Bronchitis | RSV Influenza A y B Parainfluenza Coronavirus |
Whistles Dyspnoea Temperature |
| Broncho-pneumonitis | RSV Influenza A y B Parainfluenza |
Whistles Alveolal Crepitations Dyspnoea Temperature |
| Pneumonia | Coronavirus RSV Influenza A y B Parainfluenza Adenovirus |
Alveolal Crepitations Dyspnoea Temperature |
Βιβλιογραφία: http://www.nhs.uk/conditions/Respiratory-tract-infection/Pages/Introduction.aspx
For more information on CLART PneumoVir contact:
diagnostics@aenorasis.com
The information referred to for general information and informing the public and in any case can not replace a doctor or other suitably qualified health professional. The responsibility of the media carries by ENORASIS SA
